N,N-Dimethylacetamide CAS 127-19-5

N,N-Dimethylacetamide (DMAc), with the CAS number 127-19-5, is a versatile organic compound widely used as a solvent in various industrial and scientific applications.
Chemical Properties
Molecular Formula: C₄H₉NO
Molecular Weight: 87.12 g/mol
Boiling Point: Approximately 165-166°C
Melting Point: About -17°C
Density: Approximately 0.945 g/cm³
DMAc is a colorless, water-miscible liquid that exhibits a low vapor pressure and is relatively unreactive, making it suitable for a range of applications in organic synthesis and polymer production.
Applications
N,N-Dimethylacetamide is utilized in:
Polymer Synthesis: It is effective in dissolving various polymers, including polyacrylonitrile, polyvinyl chloride, and polyamides, which are crucial in the production of fibers and plastics.
Organic Reactions: As a polar aprotic solvent, DMAc is employed in numerous organic reactions, facilitating the synthesis of organic compounds and serving as a solvent in chromatography and electrophoresis techniques.
Pharmaceuticals: DMAc is also used in the pharmaceutical industry as a solvent for drug formulations and as an excipient due to its FDA approval.
Safety and Handling
While N,N-Dimethylacetamide is widely used, it is essential to handle it with care due to potential health risks. It can cause irritation upon contact with skin and eyes, and inhalation of vapors may lead to respiratory issues. Proper safety measures, including the use of personal protective equipment, are recommended when working with this chemical.
In summary, N,N-Dimethylacetamide is a crucial solvent in various fields, particularly in organic chemistry and materials science, due to its favorable physical properties and broad applicability.