N,N-Dimethylformamide (DMF), with the CAS number 68-12-2, is a versatile organic solvent widely utilized in various industrial and laboratory applications. It is characterized by its polar aprotic nature, which allows it to dissolve a broad range of substances, making it particularly valuable in chemical synthesis and research.
Chemical Properties
Chemical Formula: HCON(CH₃)₂
Molecular Weight: Approximately 73.09 g/mol
Boiling Point: 153 °C
Melting Point: -61 °C
Flash Point: 58 °C
DMF is miscible with water and most organic solvents, which enhances its utility in diverse chemical processes.
Applications
DMF is employed in several key areas:
Solvent in Chemical Reactions: It serves as a solvent for various organic reactions, including peptide synthesis and polymer production. Its ability to stabilize reactive intermediates makes it an essential medium in many synthetic pathways, such as the Swern oxidation.
Industrial Uses: DMF is extensively used in the production of synthetic leather, fibers, and films due to its low volatility and excellent solvency properties. It aids in creating homogeneous mixtures essential for these applications.
Research and Development: In academic settings, DMF is valued for its role in facilitating reaction conditions and improving the solubility of reactants, which is crucial for the synthesis of pharmaceuticals and other complex molecules.
Safety and Handling
While DMF is a powerful solvent, it is important to handle it with care due to its potential health risks. It is known to induce liver toxicity and is classified as a hazardous substance. Proper safety measures, including the use of personal protective equipment and adequate ventilation, are essential when working with DMF.
In summary, N,N-Dimethylformamide (CAS 68-12-2) is a critical solvent in both industrial and laboratory settings, known for its excellent solvency and versatility in chemical reactions. However, safety precautions must be observed due to its toxicological profile.
N,N-Dimethylformamide CAS 68-12-2
CAS No. 68-12-2
Other Name :
Dimethyl formamide;
Formyldimethylamine;
DMF;
DMFA
MF :C3H7NO