Benzyl chloride, with the CAS number 100-44-7, is an aromatic organochlorine compound that serves as a significant chemical intermediate in various industrial applications. It is a colorless liquid with a pungent odor and is slightly soluble in water, but miscible in organic solvents such as ethanol and chloroform.
Chemical Properties and Production
Molecular Formula: C₇H₇Cl
Molecular Weight: 126.58 g/mol
Boiling Point: Approximately 179°C (354°F)
Freezing Point: -45°C
Benzyl chloride is primarily produced through the gas-phase photochemical reaction of toluene with chlorine, yielding about 100,000 tonnes annually. This reaction involves free radical processes and can also produce side products like benzal chloride and benzotrichloride.
Uses
Benzyl chloride is utilized in the synthesis of various compounds, including:
Benzyl Alcohol: Used in pharmaceuticals and cosmetics.
Benzyl Esters: Employed as plasticizers and flavorants.
Phenylacetic Acid: A precursor for pharmaceuticals.
Benzyl Ethers: Commonly used in organic synthesis as protecting groups for alcohols.
Additionally, it is involved in the production of quaternary ammonium salts, which are used as surfactants, and in the treatment of fibers.
Health and Safety Considerations
Benzyl chloride is classified as a hazardous substance. Exposure can occur through inhalation, skin contact, or ingestion, leading to irritation of the eyes, skin, and respiratory tract. Prolonged exposure may result in more severe health effects, including potential carcinogenicity, as indicated by studies showing increased tumor incidences in animal models. Therefore, appropriate safety measures should be taken when handling this chemical, particularly in occupational settings.
In summary, benzyl chloride is a versatile chemical with significant industrial applications, but it requires careful handling due to its hazardous nature.
Benzyl chloride CAS 100-44-7
CAS No.100-44-7
Other Name:alpha-Chlorotoluene
MF:C7H7Cl