Tetrahydrofuran CAS 109-99-9

Tetrahydrofuran (THF), with the CAS number 109-99-9, is a colorless, polar aprotic solvent widely used in various industrial and laboratory applications. It is classified as a heterocyclic compound and has the molecular formula C₄H₈O, with a molecular weight of 72.11 g/mol.
Properties of Tetrahydrofuran:
Physical State: THF is a clear, colorless liquid with a low viscosity and an ethereal odor.
Boiling Point: Approximately 66°C.
Freezing Point: About -108.5°C.
Water Miscibility: Tetrahydrofuran is miscible with water, which enhances its utility as a solvent in various chemical processes.
Uses of Tetrahydrofuran:
Solvent: THF is primarily used as a solvent in organic synthesis, particularly in the preparation of polymers and as a reaction medium for Grignard reagents and other organometallic compounds.
Industrial Applications: It serves as a solvent for coatings, varnishes, adhesives, and in the production of polyvinyl chloride (PVC) and other plastics.
Laboratory Use: Tetrahydrofuran is commonly employed in laboratories for various chemical reactions due to its ability to dissolve a wide range of substances.
Safety Considerations:
Tetrahydrofuran can form explosive peroxides upon prolonged exposure to air and light, and it reacts violently with strong oxidants and bases, posing fire and explosion hazards. Proper handling and storage conditions are essential to mitigate these risks.
In summary, tetrahydrofuran is a versatile and important solvent in both industrial and laboratory settings, valued for its unique properties and wide range of applications.