Dimethyl Sulfoxide (DMSO): A Safe and High-Performance Solvent for Agricultural Applications

Shandong Xuchen Chemical Technology Co., Ltd. is a leading domestic producer and supplier of dimethyl sulfoxide (DMSO), with an annual sales volume exceeding 10,000 tons. 

We are committed to providing high-quality products and exceptional service to our customers.

In collaboration with Toray Group (a Sino-Japanese joint venture utilizing Japanese Toray technology to produce high-purity DMSO), we ensure the supply of premium-grade DMSO, particularly for electronic applications. Toray Group’s DMSO, certified by ISO 9001, holds a 60% market share in the electronic-grade sector and achieved a 10.65% year-on-year growth in 2023.

Debunking Myths: DMSO’s Safety in Agrochemistry

DMSO is a versatile and efficient solvent with a long history of use. However, concerns about its skin permeability have hindered its adoption in agrochemical formulations. These concerns stem from studies conducted in the 1960s and 1970s, which highlighted DMSO’s transdermal properties—beneficial in pharmaceuticals but perceived as a risk in agriculture.

The Reality?
DMSO’s skin absorption characteristics are comparable to those of other commonly used agrochemical solvents, such as N-methyl-2-pyrrolidone (NMP), which faces stricter regulations due to its reproductive toxicity. Unlike NMP—now restricted in Europe and under increasing EPA scrutiny—DMSO poses no such risks.

Other solvents like propylene glycol (PG)ethylene glycol, and glycol ethers also exhibit skin absorption. However, proper personal protective equipment (PPE) ensures safety during formulation. Moreover, once diluted in spray tanks, DMSO hydrates completely, losing its skin-penetrating properties—a finding supported by Rutgers University’s Drug Delivery Laboratory.

In 2022, the EPA (40 CFR 180.920) removed all restrictions on DMSO as a pre-harvest inert ingredient, confirming its safety in agricultural use.

Why Choose DMSO?

As a polar aprotic solvent, DMSO offers unique advantages, making it an ideal replacement for NMP and other controversial solvents:

Superior Solubility – Dissolves a wide range of active ingredients, including water-insoluble compounds, making it perfect for emulsifiable concentrates (ECs)dispersible concentrates (DCs), and other advanced formulations.

Eco-Friendly & Non-Toxic – Unlike NMP, DMSO is not a reproductive toxin, exhibits low environmental impact, and is biodegradable.

Enhanced Efficacy – Studies show that agrochemicals formulated with DMSO improve active ingredient performance, reducing application rates while boosting effectiveness.

Low Volatility & Residue – Unlike volatile organic solvents, DMSO minimizes emissions and residue, supporting sustainable agriculture.

Conclusion

DMSO stands out as a safe, high-performance solvent for agrochemical applications, backed by scientific research and regulatory approval. At Shandong Xuchen Chemical Technology Co., Ltd., we provide top-tier DMSO solutions tailored to modern agricultural needs.

For premium-quality DMSO and expert support, partner with us today!

Shandong Xuchen Chemical Technology Co., Ltd.
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